I currently work with an adult male (aged 60) who , as far as we know < has never been treated in any way. nHe has intellectual disabilties and is very difficult to work with. nCommunication skills are very poor but he appears to be in some kind of pain and is irritable and occassionally has mood swings and temper tantrums. nAdvice from his dietician would indicate that changing his diet and taking the PKU drinks will hopefully reduce many of his problems but not all. his most recent levels were 1,800 !!!!