Just wanted to let you know that i have responded to Kuvan wonderfully. I take only 4 pills a day,and started in Nov. My PHE then was 16.9.Now it is 9.something. I am still a strong vegan.I think probably cause i don’t care for any type of meat,poultry,and fish products. Plus no more formula that alone is a blessing. I hope anyone who trys Kuvan has a good response to it.